Research Article

A review of vulvar carcinoma at Groote Schuur hospital for the period 2002 to 2012 with particular emphasis on HPV-related disease

Published in: Southern African Journal of Gynaecological Oncology
Volume 12 , issue 1 : Entrepreneurship and Africa’s Cultural Context , 2024 , pages: 17–22
DOI: 10.1080/20742835.2020.1763032
Author(s): Francisca E Loggenberg , South Africa, Tracey S Adams , South Africa,
Keywords: vulvar carcinoma, human papilloma virus, vulvar intraepithelial neoplasm, human immunodeficiency virus, squamous cell carcinoma, multifocal disease,
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Abstract

Background: Vulvar carcinoma is rare and ranks fourth amongst the gynaecological malignancies. GLOBOCAN reported 44 235 new cases in 2018. There has been a rise in the number of cases of vulvar carcinoma in recent years and younger women are being affected by the disease. This rise is thought to be the result of more women being infected with human papilloma virus (HPV). HPV has been implicated in one of the pathways leading to the development of vulvar carcinoma. This study aims to review the cases of vulvar carcinoma at Groote Schuur Hospital and places particular emphasis on HPV-related disease.
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